CLINICAL TRIALS

If you would like your clinical trial listed on our website, please contact maryangela@gimotility-agmd.org to receive our Clinical Study Announcement Application.

RESEARCH MATCH

The Association of Gastrointestinal Motility Disorders is collaborating with ResearchMatch.org to share information about access to clinical trials and educate the public about gastrointestinal disorders.

You can listen to the presentation here, https://youtu.be/bhBdOHgJj7M. We encourage you to also check out their stories about research studies and clinical trial participation: https://medium.com/researchmatch/tagged/research.

We are grateful To ResearchMatch for the opportunity!

CYCLIC VOMITING CLINICAL TRIALS

A Randomized, Double-Blind, Placebo Controlled Study to Evaluate the Safety and Efficacy
of Staccato Granisetron (AZ-010) for the Acute Treatment of Moderate to Severe Cyclic Vomiting Syndrome.

This study has 4 parts: 3 clinic visits and 1 at-home treatment period for up to 12 weeks. The first 2 visits are to determine eligibility and safety to participate in the trial. Participants will treat 1 CVS episode at home during the 12-week at home treatment period and will then return to the clinic for a safety follow up visit.

This is a multi-center study in the US. Please visit https://www.cvshope.com to find the study center nearest to you.

GASTROPARESIS CLINICAL TRIALS

Gastroparesis Registry 2 (GpR2): Continuation of the NIDDK Registry for the Characterization and Clinical Course of Gastroparesis Patients

The Gastroparesis Registry 2 is an observational study of patients with gastroparesis. This is the second registry study of gastroparesis started by the Gastroparesis Clinical Research Consortium funded by NIH. People with gastroparesis suffer from nausea, vomiting, stomach pain, feeling full after eating and/or losing weight. Why people develop gastroparesis is not known. People with diabetes, prior stomach surgery, or who have had certain viral infections seem to be at greater risk of developing this condition. The purpose of this study is to better understand gastroparesis and data collected may improve the understanding of the condition to enable better diagnosis and treatment.

We are seeking adults (18 and older) with symptoms of gastroparesis (nausea, vomiting, early satiety, fullness, abdominal pain). About 1000 people will take part in this study at 9 medical centers participating in this research study across the country. You will not receive drugs or medications as part of the Gastroparesis Registry 2. Study-related visits and procedures will be provided at no cost to you.

For more information about this study, please contact the study coordinator at 410-550-6871.

Diabetes and Idiopathic Gastroparesis Efficacy, Safety and Tolerability Study (DIGEST)

We are seeking adults 18 to 75 years of age with a diagnosis of idiopathic or diabetic gastroparesis. This research study is being done to see how well people with gastroparesis tolerate an investigational study drug called velusetrag, to see how well it works to treat symptoms of gastroparesis, to determine how safe it is, and to measure how much of it gets into the blood. This study will look at whether taking velusetrag is better than a placebo in improving the symptoms of diabetic and idiopathic gastroparesis. This study will also look at the usefulness of having participants complete a questionnaire about their gastroparesis symptoms.

For more information about this study and to learn how you can participate, please contact the study manager at 410-550-6871.